t-PA-PAI-1 Complex

To understand how fibrinolysis is regulated, in general and in individual patients, we need to know the circulating in vivo concentration of active t-PA, active PAI-1, and t-PA-PAI-1 complex. Knowing the concentrations of both t-PA-PAI-I complex and active PAI-1 is crucial to understanding how the level of active t-PA is being controlled.

TECHNOZYM^® t-PA - PAI-1 Complex ELISA Kit

For determination of t-PA-PAI-1 complexes in plasma. The kit is based on a monoclonal antibody directed against t-PA as a catching antibody for t-PA - PAI-1 complexes and a peroxidase-labeled     monoclonal anti-PAI-1 antibody used for the detection of bound t-PA - PAI-1 complexes.