Thrombophilia

Protein S

Protein S (S for Seattle) is a vitamin K-dependent plasma glycoprotein synthesized in the endothelium. In the  circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein (C4BP). The best characterized function of Protein S is its role in the anti coagulation pathway, where it  functions as a cofactor to Protein C in the inactivation of Factors Va and VIIIa. Only the free form has cofactor activity.

 

Protein S deficient plasma [RUO]

Lyophilized PS deficient plasma, immunodepleted

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5341031 2 x 1 ml Download Insert