Protein C (PC)
Protein C is a vitamin K dependent serine protease which, when activated, inhibits coagulation by inactivating the clotting factors V/Va and VIII/VIIIa. Additionally, protein C has been shown to have profibrinolytic activity. Hereditary, heterozygous protein C deficiency has been found to be associated with an increased risk of venous thrombosis and hereditary, homozygous total protein C deficiency has been found in neonates with purpura fulminans. Reduced levels of protein C have been found in association with vitamin K deficiency and during coumarin therapy.
TECHNOCHROM® Protein C
Is an enzymatic reagent kit for the determination of Protein C (PC) activity.
Test Principle: (Protac®)
Protein C ———— Protein Ca
Pad-Pro-Arg-pNA . AcOH ———— Pad-Pro-Arg-OH . AcOH+p-nitroaniline
TECHNOCLOT® Protein C
Is a reagent kit for the clotting determination of Protein C (PC) activity.
TECHNOZYM® Protein C ELISA
The TECHNOZYM® PC ELISA allows the determination of Protein C (PC) antigen plasma levels in patients with thrombotic tendencies. The assay is a double polyclonal antibody “sandwich” assay.
TECHNOZYM® Protein C ELISA Kit
12 x 8 anti PC strips
1 x 0.3 ml anti PC Conjugate
1 x 80 ml Wash Buffer Concentrate
1 x 90 ml Incubation Buffer
1 x 12 ml TMB Substrate
1 x 12 ml Stop Solution
7 x 0.5 ml Calibrators and Controls