Thrombophilia

Protein C (PC)

Protein C is a vitamin K dependent serine protease which, when activated, inhibits coagulation by inactivating the clotting factors V/Va and VIII/VIIIa. Additionally, protein C has been shown to have profibrinolytic activity. Hereditary, heterozygous protein C deficiency has been found to be associated with an increased risk of venous thrombosis and hereditary, homozygous total protein C deficiency has been found in neonates with purpura fulminans. Reduced levels of protein C have been found in association with vitamin K deficiency and during coumarin therapy.

TECHNOCHROM® Protein C

Is an enzymatic reagent kit for the determination of Protein C (PC) activity.

Test Principle:            (Protac®)

                            Protein C ————    Protein Ca

                                                                   (Protein Ca)
                            Pad-Pro-Arg-pNA AcOH ————    Pad-Pro-Arg-OH . AcOH+p-nitroaniline

TECHNOCLOT® Protein C

Is a reagent kit for the clotting determination of Protein C (PC) activity.

TECHNOZYM® Protein C ELISA

The TECHNOZYM® PC  ELISA allows the determination of Protein C (PC) antigen plasma levels in patients with thrombotic tendencies. The assay is a double polyclonal antibody “sandwich” assay.

TECHNOCHROM® Protein C

3 x 1 ml Substrate PCa-2
3 x 1 ml Protein C Activator
1 x 60 ml Protein C Buffer
3 x 1 ml Standards (~0.25-1.25 U/ml)

REF Package Size Insert
5341013 ~ 30 tests Download Insert

TECHNOCLOT® Protein C

2 x 1 ml Protein C depleted plasma
2 x 1 ml Protein C Activator
1 x 17 ml Imidazole Buffer

REF Package Size Insert
5346200 ~ 20 tests Download Insert

TECHNOZYM® Protein C ELISA Kit

12 x 8 anti PC strips

1 x 0.3 ml anti PC Conjugate

1 x 80 ml Wash Buffer Concentrate

1 x 90 ml Incubation Buffer

1 x 12 ml TMB Substrate

1 x 12 ml Stop Solution

7 x 0.5 ml Calibrators and Controls

REF Package Size Insert Lot
TC12021 96 tests Download Insert 120212B8, 120213B8

Protein C deficient plasma

Lyophilized PC deficient plasma, immunodepleted.

REF Package Size MSDS Insert
5346806 2 x 1 ml Download MSDS Download Insert

Substrate Pca-2

Chromogenic Substrate for the determination of protein C

REF Package Size MSDS Insert
5353011 2 x 6 mmol Download MSDS Download Insert

Protac®

Protac®, a highly purified extract from the venom of the snake Agkistrodon Contortrix, is a fast and direct activator of Protein C.

REF Package Size Insert
5346212 5 x 1 ml Download Insert

Protein C Buffer

Buffer for the chromogenic determination of protein C activity.

REF Package Size MSDS Insert
5341052 60 ml Download MSDS Download Insert