The Fibrinogen reagent of Technoclone is a modified Clauss Reagent with a high thrombin concentration to make the test virtually insensitive to heparin and to enhance clot detection.
The Fibrinogen is used :
· in the diagnosis of DIC
· in the diagnosis of liver failures
· to detect qualitatively abnormalities of fibrinogen
· to determine quantitatively deficiency of fibrinogen
A calibration curve of clotting time versus concentration in g/dL is first determined with a plasma having a known concentration of fibrinogen, such as Coagulation Reference. The fibrinogen concentration of patient samples are read off the calibration curve.