Coagulation

Fitzgerald Trait Plasma, native [CE]

Fitzgerald Trait Plasma is a lyophilized and stabilized human high molecular weight kininogen deficient plasma. It is used in the determination of High Molecular Weight-Kininogen defects. HMW-kininogen deficient plasma exhibit a prolonged coagulation time in the aPTT test. The aPTT can be corrected in vitro by the addition of factor XII deficient plasma or Fletcher Trait Plasma (prekallikrein deficient plasma).
 

Fletcher Trait Plasma, immundepl. [CE]

Fletcher Trait Plasma is a lyophilized and stabilized human pre-kallikrein deficient plasma. It is used in the determination of high pre-kallikrein deficiency based on an aPTT. A deficiency in pre-kallikrein will prolong the activated partial thromboplastin time (aPTT) considerably but does not usually result in the expected haemorrhagic tendency. This abnormality in the activating phase of the aPTT can be corrected in vitro by adding factor XII deficient plasma or Fitzgerald Trait Plasma (HMW-Kininogen deficient plasma).