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Literature

Literature for Thrombin Generation

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Protocols

  • TECHNOTHROMBIN® TGA Mouse Protocol



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Literature

  • Roemisch J. et al.
    Identification of Activated FXI as the Major Biochemical Root Cause in IVIG Batches Associated with Thromboembolic Events. Analytical and Expermimental Approaches Resulting in Corrective and Preventive Measures Implemented into the Octagam® Manufacturing Process



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  • C. Ay et al.
    Thrombin generation in patients with a bleeding tendency of unknown origin
    Ann Hemtaol, DOI 10.1007/s00277-011-1201-8, 2011
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  • C. Ay et al.
    Prediction of Venous Thromboembolism in Patients With Cancer By Measuring Thrombin Generation: Results From the Vienna Cancer and Thrombosis Study
    JOURNAL OF CLINICAL ONCOLOGY, DOI: 10.1200/JCO.2010.32.8294, 2010
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  • Prati C. et al.
    Thrombin generation in ankylosing spondylitis
    Clinical Rheumatology, DOI 10.007/s10067-010-1552-x

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  • Eichinger S. et al.
    Risk Assessment of Recurrence in Patients with Unprovoked Deep Vein Thrombosis or Pulmonary Embolism: The Vienna Prediction Model
    Circulation 2010; 121; 1630-1636
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  • Ettinghausen et al.
    Early long-term FEIBA prophylaxis in haemophilia A patients
    with inhibitor after failing immune tolerance induction:
    A prospective clinical case series
    Haemophilia (2010), 16, 90?100 DOI: 10.1111/j.1365-2516.2009.02116.x
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  • Dietrich W. et al.
    CU-2010?A Novel Small Molecule Protease Inhibitor with
    Antifibrinolytic and Anticoagulant Properties
    Anesthesiology 2009; 110:123?30
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  • Heger A. et al.
    Biochemical quality of the pharmaceutically licensed plasma OctaplasLG after implementation of a novel prion protein (PrPSc) removal technology and reduction of the solvent/detergent (S/D) process time
    Vox Sanguinis (2009) 97, 219?225, DOI: 10.1111/j.1423-0410.2009.01190.x
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  • Leyla Ay et al.
    Thrombin generation in morbid obesity: significant reduction after weight loss
    2009 Journal of Thrombosis and Haemostasis doi: 10.1111/j.1538-7836.2010.03766.x
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  • Lopez-Vilchez I. et al.
    Serotonin enhances platelet procoagulant properties and their activation induced during platelet tissue factor uptake
    Cardiovascular Research, doi:10.1093/cvr/cvp205
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  • Haubold K. et al.
    Tissue factor procoagulant acitivty of plasma micropaticles is increased in patients with early-stage prostate cancer
    Schattauer 2009, doi: 10.1160/TH08-10-0654
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  • Buyue et al.
    Fucosylated chondroitin sulfate inhibits plasma thrombin generation via targeting of the factor IXa heparin-binding exosite
    Blood 2009, doi:10.1182/blood-2009-02-203661
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  • Buyue et al.
    Thrombin generation and venous thrombosis. The heparin-binding exosite of factor IXa is a critical regulator of plasma

    Blood 2008, doi:10.1182/blood-2008-01-136820

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  • Weeterings C. et al.
    The glycoprotein Ib-IX-V complex contributes to tissue factor independent thrombin generation by recombinant factor VIIa on the activated platelet surface
    Blood 2008; 112: 3227-3233

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  • Buyue Y. et al.
    The heparing-binding exosite of factor IXa is a critical regulator of plasma thrombin generation and venous thrombosis
    Blood 2008; 112: 3234-3241
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  • Lechner D. et al.
    Comparison between didiopathic deep vein thrombosis of the upper and lower extremity regarding risk factors and recurrence
    JTH 2008; 6: 1269-1274
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  • Weeterings C. et al.
    The glycoprotein lb-IX-V complex contributes to tissue factor-indipendent thrombin generation by recombinant factor VIIa on the activated platelet surface
    Blood 2008; doi: 10.1182/blood-2008-02-139113
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  • Hamd R. et al.
    Increased thrombin generation in women with a history of preeclampsia
    Thromb. Res. 2008; doi: 10.1016/j. thromres. 2008.03.022
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  • Lechner D. et al.
    Chemotherapy-induced thrombin generation via procoagulant endothelial microparticles is independent of tissue factor activity
    Journal of Thrombosis and Haemostasis 2007, 5: 2445?2452

     
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  • Orbe J. et al.
    Increased thrombin generation after acute versus chronic coronary desease as assessed by the thrombin generation test
    Thromb. Haemost. 2008; 382-387
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  • Lechner D. et al.
    Chemotherapy-induced thrombin generation via procoagulant endothelial micrparticles is independent of tissue factor activity
    JTH, 2007; 5:2445-2452
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  • Leryer A. et al.
    Cellular Origins and Thrombogenic Activity of Microparticels Isolated from Human Atherosclerotic Plaques
    Journal of the American College of Cardiology, 2007, Vol. 49, No. 7; 772-777
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  • Suman G. et al.
    Blood coagulation activation and fibrinolysis during a downhill marathon run 
    Blood Coagulation and Fibrinolysis (2007), 18, 435-440  

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  • Siegemund A. et al.
    Thrombin Generation in Children with Hemophilia and VWD ? Comparing a Fluorimetric Method and ROTEM
    2006, 37th Hemophilia Symposium Hamburg

      


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  • Hron G. et al. 

    Identification of Patients at Low Risk for Recurrent Venous Thromboembolism by Measuring Throbin Generation

    JAMA 2006, July 26, 2006 - Vol 296, No. 4, 397-402  

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  • Váradi K. et al. 
    Thrombin generation assay and other universal test for monitoring haemphilia therapy
    Haemophilia 2004, 10, (Suppl. 2), 17-21  

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Orals

  • K. Váradi, P. Turecek 
    Thrombin Generation for Hemophilie Treatment Monitorin
    Pekelharing Symposium, Leipzig 2007



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  • Wiens L. 
    Influence of pre-analytic variables on thrombin generation
    GTH Dresden 2007
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  • Male C. et al. 
    Thrombin Generation Assay for Monitoring FVIII Inhibitor Bypassing Agent
    GTH Dresden 2007, FV26
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  • Kyrle P. et al. 
    Thrombosis generation and venous thrombosis
    52nd Annual Scientific and Standardization Committee Meeting, Oslo 2006
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  • Kyrle P. et al. 
    Identification of patients with a low risk of recurrent venous thromboembolism by measuring thrombin generation. 
    GTH Basel 2006, V65
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  • Isobe H. et al. 
    Apoptotic microparticles derived from endothelial cells, smooth muscle cells and monocytes induce thrombin generation via different coagulation pathways.
    GTH Basel 2006, V113
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Posters

  • S. Testa et al.
    Carbetocin increases thrombin generation after cesarean section
    SISTE 2010, Bologna



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  • Evangelos L. et al.
    Persistent Inhibiton of Thrombin Generation After Intravenous Administration of Enoxaparin in Primates
    Thrombosis Milano 2010
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  • Adiguzel C. et al.
    Generic Versions of Argatroban can be Differentiated from Branded Argatroban in the Thrombin Genration Assays (TGA)
    Thrombosis Milano 2010
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  • C. Kluft et al.
    Different variants of the thrombin generation test (TGT) show differences in sensitivity to microparticels and the contact system: analysis of ECA-surveys
    Thrombosis Milano 2010
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  • B. Myers et al.
    Preliminary results of baseline thrombin generation and firbrinolysis in women with previous pregnancy-associated venous thrombosis: thrombin generation appears increased and fibrinolytic activity reduced compared to healthy femal controls
    ISTH 2009
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  • Riddell et al.
    Comparison of Three different Thrombin Generation Assays in Patients with Haemophilia
    ISTH 2009
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  • Vlieg et al.
    Thrombophilia, hypercoagulability, and environment, and the risk of venous thrombo-embolism (THE-VTE study)
    ISTH 2009
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  • Speer O. et al.
    Apoptosis in platelets from pediatric patients with acute immune thrombocytopenia purpura is ameliorated by IVIg
    ASH 2008
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  • Ryland JK. et al.
    A comporative assesment of two Thrombin generation assays in the analysis of samples from post-thrombotic patients
    BSHT 2008
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  • Berntop E. et al.
    Thrombin generation assay for optimizing hamophilia A therapy in patients with inhibitor
    WFH 2008, Istanbul
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  • Eichinger S. et al.
    Effects of Recombinant Factor VIIa (NovoSeven®) on Restoring Thrombin Generation in Patients with Hemophilia A and Antibodies to Factor VIII
    WFH 2008, Istanbul
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  • Haushofer A. et al.
    Comparison of three commercial thrombin genration assays in different patients settings
    GTH 2008
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  • Kaufmann V. et al.
    Role of Microparticels in Thrombin Genration in Patients at Risk of Atherothrombosis
    ASH 2007
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  • Wiens L. et al.
    Thrombin Generation in mammal
    OEGKL DGKL 2007
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  • Siegemund T. et al. 
    Inhibitor against F V - Monitoring with thrombin generation
    ISTH Geneva 2007
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  • Siegemund T. et al. 
    Monitoring NovoSeven therapie with Different Methods
    ISTH Geneva 2007
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  • Eichinger S. et al. 
    Effects of Recombinant Factor VIIa (NovoSeven®) on Restoring Thrombin Generation in Patients with Hemophilia A and Antibodies to Factor VIII
    ISTH Geneva 2007
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  • Pock K. et al. 
    Thrombin generation capacity is impaired in methylene-blue (MB) treated plasma units compard to single-donor FFP, a pharmaceutically licensed cogulation active and solvent-detergent (S/D) treated plasma product and a universally applicable S/D plasma under development
    ISTH Geneva 2007
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  • Kaufmann V. et al. 
    Measurement of thrombin generation in patients at risk atherothormbosis
    ISTH Geneva 2007
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  • Kaufmann V. et al. 
    Micropartikels in Thrombin Generation - A Significant Parameter Influencing Peak Thrombin Levels
    ISTH Geneva 2007
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  • Lösche W. et al. 
    Thrombin generation in on-pump cardiac surgery patients
    GTH Dresden 2007
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  • Kaufmann V .et al. 
    Mikroparticles are a major determinant for thrombin generation measured by TECHNOTHROMBIN® TGA
    ASH Orlando 2006
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  • Wiens L. et al. 
    Influence of pre-analytic variables on thrombin generation
    DGKL Mannheim 2006
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  • Wiens L. et al. 
    Thrombin generation during pregnancy and postpartum
    DGKL Mannheim 2006
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  • Kaufmann V. et al. 
    TECHNOTHROMBIN® TGA a novel Thrombin Generation Assay suitable for the new routine coagulation analyzer Ceveron® alpha  
    WFH, Vancouver 2006
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  • H. Isobe et al.
    Evaluation of TECHNOTHROMBIN® TGA in patients with venous or arterial thrombotic tendencies: Circulating micro particles as possible causative factors.
    International Congress on Thromobis, Tel Aviv 2006
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  • Wiens L. et al.
    Thrombin Generation: First Experiences Using Two Different Assays: Endogeneous Thrombin Potential (ETP, Dade Behring) and TECHNOTHROMBIN® TGA (Technoclone)
    GTH Basel 2006, P140


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  • Kaufmann V. et al.
    Validation of the thrombin generation assay TECHNOTHROMBIN® TGA
    GTH Basel 2006, P286
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  • Isobe H. et al. 
    Apoptotic microparticles derived from endothelial cells, smooth muscle cells and monocytes induce thrombin generation via different pathways.
    ASH Atlanta 2005, P148
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  • Váradi K. et al. 
    Applications of Thrombin Generation Assay in Characterizing FVIII Inhibitor Bypassing Agents
    ISTH Sydney 2005 
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